Human Genetics SIG          

The ISCBFM Human Genetics SIG will promote research and enhance collaboration for studies involving human genetics. This SIG is developed to bridge collaboration between members of the ISCBFM and the International Stroke Genetics Consortium (ISGC), an international collaborative with over 150 investigators throughout the world, studying the genetics of cerebrovascular phenotypes.  The ISGC, founded in 2007, meets twice per year to enable international collaboration for a large number of human genetics studies, and has successfully identified numerous loci associated with a variety of cerebrovascular phenotypes including ischemic stroke, intracerebral hemorrhage, small vessel disease, and other neuroimaging phenotypes.  As increasing numbers of genome-wide significant loci are identified, collaboration with more basic investigators to understand molecular mechanisms underlying these associations will be needed.  In addition, human genetics might provide translational insight into genetic findings from cellular and animal models.  Thus, the Human Genetics SIG will serve as a bridge to enhance collaboration across these organizations.

The mission of the ISCBFM Human Genetics SIG is to promote human genetics research and to enhance collaboration between geneticists, epidemiologists, clinicians, physiologists, molecular biologists, and animal modelers, in order to understand the human relevance of fundamental findings related to cerebrovascular physiology and pathology. Moreover, human genetics may provide strong support for the translational of potential drug targets to clinical applications.

Human Genetics SIG Chair:
Jin-Moo Lee      [email protected]

Recent and Planned Activities:

  • ISGC Fall Workshop, Washington, D.C., November 8-9, 2018 at the National Museum of the American Indian. 100 investigators from throughout the world will meet to discuss progress on the latest studies involving human genetics of stroke and cerebrovascular disease.

  • ISGC Spring Workshop, Queens College, Oxford, April 11-12, 2019.


How to Join:
If you want to become involved with the Human Genetics SIG click the link below. Your participation is welcome! 

Click here to join!